• Progynova 2mg Tablets (84s)

  • Progynova 2mg Tablets
  • 1 pack = 84 Tablets £30.00
    2 packs = 168 Tablets £49.00
  • Progynova is a continuous oestrogen alone hormone replacement therapy (HRT), containing a naturally occurring form of the female hormone oestrogen, estradiol valerate. Progynova comes in the form of a tablet. This type of HRT is most suitable for you if you have had a hysterectomy (removal of the uterus or womb). If you have not had a hysterectomy, you should also take another hormone called progestin whilst taking HRT, to prevent complications associated with taking oestrogen alone.

    The estradiol helps to make up for the body’s reduced levels of oestrogen. Offsetting this balance will help to:

    • Provide relief of the symptoms that occur after the menopause, such as hot flushes.
    • Prevent osteoporosis (fragile bones) which can develop after menopause. The falling levels of oestrogen can promote thinning of the bones and makes them more prone to breaking. Supplementing the oestrogen can help to prevent bone loss and fractures, which can occur in women in the years following menopause.

    Take one tablet each day. For ease, use the arrows on the pack and follow the direction they take until the pack is empty. Once you have finished a foil strip, start a new strip, taking the tablet on the day indicated.

    If you are changing from another type of HRT, start taking Progynova once you have finished the pack of HRT you are currently taking. If you are not currently taking another type of HRT, you should begin when convenient. If you are still having periods, take your first tablet on the first day of bleeding.

    Take one tablet daily. Swallow this tablet whole with a drink either with or without food.

    Your tablet should be taken at around the same time each day; getting into a rhythm should help you to remember to take it.

    If you forget to take a dose at your usual time the missed dose should be taken provided no more than 12 hours have elapsed since you last took a tablet. If your dose is more than 12 hours late, the forgotten dose should be skipped and your next dose should be taken at your usual time. If you take a double dose, this could lead to breakthrough bleeding.

    Please note: if you ever need to have major surgery, please inform us as soon as you know, so that our doctor can advise you on whether to stop taking this medication.

    Your need for HRT should be reviewed by your doctor at least once every twelve months.

    The following side effects can affect individuals in different ways, it does not mean that all will be affected:

    Common (may affect up to 1 in 10 people):

    • Feeling sick
    • Stomach cramps
    • Headache
    • Increase in size of fibroids in the womb
    • Breakthrough bleeding
    • Changes in weight
    • Oedema (swelling) of legs
    • Breast tenderness and enlargement
    • Mood changes
    • Changes in sex drive

    Uncommon (may affect up to 1 in 100 people):

    • Indigestion
    • Being sick
    • Flatulence
    • Gallstones and gallbladder disease
    • Feeling dizzy
    • Migraine
    • Vaginal thrush
    • Increase in blood pressure
    • Leg cramps

    Rare (may affect up to 1 in 1,000 people):

    • Loss of hair from the scalp
    • Increase in body and facial hair
    • Itchiness
    • Rashes

    The side effects listed above may not include all of the side effects reported by the medicine's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

    If you think you have experienced a side effect from the medicine you should check the patient information leaflet. This lists the known side effects and what to do if you get them. You can also get advice from your doctor, nurse or pharmacist. If they think it’s necessary they'll report it for you.

    Progynova should be used with caution if you have:

    • fibroids inside your womb
    • a growth of womb lining outside your womb (endometriosis) or a history of excessive growth of the womb lining (endometrial hyperplasia)
    • increased risk of developing blood clots (thrombosis)
    • increased risk of getting an oestrogen-sensitive cancer (such as having a mother, sister or grandmother who has had breast cancer)
    • high blood pressure
    • a liver disorder, such as a benign liver tumour
    • diabetes
    • gallstones
    • migraine or severe headaches
    • a disease of the immune system that affects many organs of the body (systemic lupus erythematosus, SLE)
    • epilepsy
    • asthma
    • a disease affecting the eardrum and hearing (otosclerosis)
    • a very high level of fat in your blood (triglycerides)
    • fluid retention due to cardiac or kidney problems

    Progynova should not be used if you:

    • have or have ever had breast cancer, or if you are suspected of having it
    • have cancer which is sensitive to oestrogens, such as cancer of the womb lining (endometrium), or if you are suspected of having it
    • have any unexplained vaginal bleeding
    • have excessive thickening of the womb lining (endometrial hyperplasia) that is not being treated
    • have or have ever had a blood clot in a vein (thrombosis), such as in the legs (deep venous thrombosis) or the lungs (pulmonary embolism)
    • have a blood clotting disorder (such as protein C, protein S, or antithrombin deficiency)
    • have or recently have had a disease caused by blood clots in the arteries, such as a heart attack, stroke or angina
    • have or have ever had a liver disease and your liver function tests have not returned to normal
    • have a rare blood problem called “porphyria” which is passed down in families (inherited)

    Progynova should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

    The patient information leaflet (PIL) is a leaflet containing specific information about medical conditions, doses and side effects. You can download a copy of the PIL here:

    Patient Info Leaflet Progynova 2mg Tablets Information Leaflet