• Evorel 50mcg Patches (8s)

  • Evorel 50mcg Patches
  • Due to the current high demand, we are currently unable to obtain this medicine from our wholesalers and have not yet been given a date for when the medicine will become available. We apologise for any inconvenience caused.
  • Evorel is a continuous oestrogen alone hormone replacement therapy (HRT), containing a naturally occurring form of the female hormone oestrogen (estradiol hemihydrate). Evorel comes in the form of a square patch, which comes in different sizes depending on the strength of the hormone. The patches release the estradiol through the skin into the bloodstream at a constant rate and are replaced twice per week.

    This type of HRT is most suitable for you if you have had a hysterectomy (removal of the uterus or womb). If you have not had a hysterectomy, you should also take another hormone called progestin whilst taking HRT to prevent complications associated with taking oestrogen alone.

    The estradiol helps to make up for the body’s reduced levels of oestrogen. Off-setting this balance will help to:

    • Provide relief of the symptoms that occur after the menopause, such as hot flushes.
    • Prevent osteoporosis (fragile bones) which can develop after menopause. The falling levels of oestrogen can promote thinning of the bones and make them more prone to breaking. Supplementing the oestrogen can help to prevent bone loss and fractures which can occur in women in the years following menopause.

    Apply a new patch twice a week (every three to four days) to your buttock or hip, below the waistline. It is best to avoid areas where clothing can cause the patch to rub off.

    Do not apply the patch to or near to the breasts.

    Each time you apply a new patch, change the site you place it and do not place the patch on that same area for at least a week.

    Before you apply the patch to your skin, make sure that your skin is clean and dry, cool, free of any powder, oily moisturise or lotion and free of cuts or irritation.

    You can keep the patch on when you have a shower or bath. If the patch falls off, wait until the skin is dry and at a normal temperature before applying a new patch. Replace the patch with a new one immediately. Replace this patch on the scheduled ‘change’ day.

    For details on applying the patch, please see the product information leaflet.

    If you ever need to have major surgery, please inform us as soon as you know, so that our doctor can advise you on whether to stop taking this medication.

    Your need for HRT should be reviewed by your doctor at least once every twelve months.

    The following side effects can affect individuals in different ways, it does not mean that all will be affected:

      Very common (may affect more than 1 in 10 patients):

      • Irritated, itchy, red skin where the patch is applied

      Common may affect up to 1 in 10 patients):

      • Red, puffy skin where the patch is applied
      • Breast pain
      • Rash or feeling itchy
      • Feeling dizzy
      • Feeling depressed
      • Headache
      • Feeling sick or having stomach pains
      • Diarrhoea
      • Pain, including pain in joints
      • Break through bleeding, spotting or periods
      • Weight gain

      Uncommon (may affect up to 1 in 100 patients):

      • Vaginal thrush
      • Flatulence
      • Being aware of your heart beat (palpitations)
      • Fuller breasts
      • Painful periods
      • Swelling of hands and feet (peripheral oedema)
      • Water retention or build-up of fluid under the skin (oedema)
      • Muscle pain
      • Allergic reactions (hypersensitivity)
      • The side effects listed above may not include all of the side effects reported by the medicine's manufacturer. For more information about any other possible risks associated with Evorel, please read the information provided with the medicine or consult your doctor or pharmacist.

    Evorel should be used with caution if you have:

    • fibroids inside your womb
    • a growth of womb lining outside your womb (endometriosis) or a history of excessive growth of the womb lining (endometrial hyperplasia)
    • increased risk of developing blood clots (thrombosis)
    • increased risk of getting an oestrogen-sensitive cancer (such as having a mother, sister or grandmother who has had breast cancer)
    • high blood pressure
    • a liver disorder, such as a benign liver tumour
    • diabetes
    • gallstones
    • migraine or severe headaches
    • a disease of the immune system that affects many organs of the body (systemic lupus erythematosus, SLE)
    • epilepsy
    • asthma
    • a disease affecting the eardrum and hearing (otosclerosis)
    • a very high level of fat in your blood (triglycerides)
    • fluid retention due to cardiac or kidney problems

    Evorel should not be used if you:

    • have or have ever had breast cancer, or if you are suspected of having it
    • have cancer which is sensitive to oestrogens, such as cancer of the womb lining (endometrium), or if you are suspected of having it
    • have any unexplained vaginal bleeding
    • have excessive thickening of the womb lining (endometrial hyperplasia) that is not being treated
    • have or have ever had a blood clot in a vein (thrombosis), such as in the legs (deep venous thrombosis) or the lungs (pulmonary embolism)
    • have a blood clotting disorder (such as protein C, protein S, or antithrombin deficiency)
    • have or recently have had a disease caused by blood clots in the arteries, such as a heart attack, stroke or angina
    • have or have ever had a liver disease and your liver function tests have not returned to normal
    • have a rare blood problem called “porphyria” which is passed down in families (inherited)

    Evorel should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

    The patient information leaflet (PIL) is a leaflet containing specific information about medical conditions, doses and side effects. You can download a copy of the PIL here:

    Patient Info Leaflet Evorel 50mcg Patches Information Leaflet