Elleste Duet Conti is a continuous combined type of Hormone Replacement Therapy (HRT), which a tablet. This type of HRT is more suitable for women whose last period was twelve months or more ago. Elleste Duet Conti’s main components are:
- estradiol (a form of oestrogen)
- norethisterone (a synthetic form of progesterone)
The estradiol helps to make up for the body’s declining levels of oestrogen, as your ovaries produce less of it in the years approaching the menopause.
Offsetting this balance can help reduce some of the more upsetting symptoms of the menopause, such as:
- irregular periods
- hot flushes
- night sweats
- mood swings
- vaginal dryness or itching
The declining level of oestrogen at menopause can also affect the bones, causing them to become thinner and more prone to breaking - a condition known as osteoporosis. Estradiol can therefore be supplemented to help prevent bone loss and fractures.
It is worth noting that oestrogen stimulates the lining of the womb and, in rare cases, this can lead to endometrial cancer. This is where norethisterone comes into action - it stops the estradiol’s womb stimulating effect, in turn reducing the risk of cancer.
If you are changing from cyclical HRT, you should begin treatment the day after finishing the oestrogen plus progesterone phase. If you are not changing from cyclical HRT, you should begin when convenient.
Take one tablet daily. Swallow this tablet whole with a drink, either with or without food.
Your tablet should be taken around the same time each day; getting into a rhythm should help you to remember to take it.
If you forget to take a dose at your usual time the missed dose should be taken provided no more than 12 hours have elapsed since you last took a tablet. If your dose is more than 12 hours late, the forgotten dose should be skipped and your next dose should be taken at your usual time. If you take a double dose, this could lead to breakthrough bleeding.
Please note: if you ever need to have major surgery, please inform us as soon as you know, so that our doctor can advise you on whether to stop taking this medication.
Your need for HRT should be reviewed by your doctor at least once every twelve months.
The following side effects can affect individuals in different ways, it does not mean that all will be affected:
Common (may affect up to 1 in 10 people):
- feeling sick
- stomach cramps
- an increase in size of fibroids in the womb
- breakthrough bleeding
- changes in weight
- oedema (swelling) of legs, breast tenderness and enlargement
- mood changes
- changes in sex drive
Uncommon (may affect up to 1 in 100 people):
- being sick
- gallstones and gallbladder disease
- feeling dizzy
- vaginal thrush
- increase in blood pressure
- leg cramps
Rare (may affect up to 1 in 1,000 people):
- loss of hair from the scalp
- increase in body and facial hair
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer. For more information about any other possible risks associated with Elleste Duet Conti, please read the information provided with the medicine or consult your doctor or pharmacist.
Elleste Duet Conti should be used with caution if you have:
- fibroids inside your womb
- a growth of womb lining outside your womb (endometriosis) or a history of excessive growth of the womb lining (endometrial hyperplasia)
- increased risk of developing blood clots (thrombosis)
- increased risk of oestrogen-sensitive cancer (the risk is increased if your mother, grandmother or sister has, or has had, breast cancer)
- high blood pressure
- a liver disorder, such as a benign liver tumour
- migraine or severe headaches
- a disease of the immune system that affects many organs of the body (e.g.systemic lupus erythematosus, SLE)
- a disease affecting the eardrum and hearing (otosclerosis)
- a very high level of fat in your blood (triglycerides)
- fluid retention due to cardiac or kidney problems
Elleste Duet Conti should not be used if you:
- have or have ever had breast cancer, or if you are suspected of having it
- have cancer which is sensitive to oestrogens, such as cancer of the womb lining (endometrium), or if you are suspected of having it
- have any unexplained vaginal bleeding
- have excessive thickening of the womb lining (endometrial hyperplasia) and this is not being treated
- have or have ever had a blood clot in a vein (thrombosis), such as in the legs (deep venous thrombosis) or the lungs (pulmonary embolism)
- have a blood clotting disorder (such as protein C, protein S, or antithrombin deficiency)
- have or recently have had a disease caused by blood clots in the arteries, such as a heart attack, stroke or angina
- have or have ever had a liver disease and your liver function tests have not returned to normal
- have a rare blood problem called “porphyria” which is passed down in families (inherited)
Elleste Duet Conti should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel think or feel that you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately and immediately stop using this medicine.
The patient information leaflet (PIL) is a leaflet containing specific information about medical conditions, doses and side effects. You can download a copy of the PIL here:
Patient Info Leaflet